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Substituted Sulfanilamidopyrimidines1

W Braker, EJ Pribyl, JT Sheehan…

文献索引:Braker et al. Journal of the American Chemical Society, 1947 , vol. 69, p. 3072,3075

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被引用次数: 20

摘要

American Chemical Society, Atlantic City, NJ, April 8 12, 1946. groups into one or more of the 4, 5-and 6-positions of the pyrimidine moiety of the 2-sulfanilamidopyrimidine type, a chemotherapeutic agent more efficacious than the aforementioned might result. In particular it was hoped that a compound would be found possessing more desirable pharmacological properties with respect to absorption, persistence in the blood, degree of acetylation, ...