DNA binding ligands targeting drug-resistant bacteria: structure, activity, and pharmacology

JA Kaizerman, MI Gross, Y Ge, S White…

文献索引：Corral, Carlos; Lasso, Ana; Lissavetzky, Jaime; Alvarez-Insua, Alberto Sanchez; Valdeolmillos, Ana M. Heterocycles, 1985 , vol. 23, # 6 p. 1431 - 1435

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被引用次数: 70

摘要

... The optimization was focused on N-terminal aromatic heterocycles and C-terminal amines ... As these small molecules (M w ≈ 550 to 750) bind at multiple functionally ... N-methyl pyrrolecarboxamide): about 150 molecules bearing modified N-terminal heterocyclic moieties ...