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Nature Neuroscience 2017-06-27

A checkpoint to pain

Michael Hirth, Jagadeesh Gandla, Rohini Kuner

文献索引:10.1038/nn.4586

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摘要

The checkpoint pathway consisting of programmed death ligand 1 (PD-L1) and its receptor, PD-1, modulates immune function in cancer and infection, but unexpectedly, it also silences pain signals in nerves.