Synthesis, crystal structure, and ESR study of a novel phosphorylated lipophilic spin trap

…, J Sun, K Liu, W Chen, W Shi, HM Wang…

文献索引：Xu, Ying-Kai; Chen, Zhong-Wei; Sun, Jian; Liu, Ke; Chen, Wei; Shi, Wei; Wang, Hong-Mei; Liu, Yang Journal of Organic Chemistry, 2002 , vol. 67, # 22 p. 7624 - 7630

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被引用次数: 33

摘要

In this article, the synthesis of a novel α-phosphorus-containing spin trap DEPPEPO [2- (diethoxyphosphoryl)-2-phenethyl-3, 4-dihydro-2 H-pyrrole-1-oxide] and the evaluation of its ability to spin-trap radicals, especially superoxide and hydroxyl radicals, are described. Single crystal X-ray structure analysis reveals that there exist a lot of intramolecular nonbonded attractive interactions in the molecule. The phenethyl group is located away ...