Alkyl piperidine and piperazine hydroxamic acids as HDAC inhibitors

…, M Porcelloni, P D'Andrea, CI Fincham, A Ettorre…

文献索引：Rossi, Cristina; Porcelloni, Marina; D'Andrea, Piero; Fincham, Christopher I.; Ettorre, Alessandro; Mauro, Sandro; Squarcia, Antonella; Bigioni, Mario; Parlani, Massimo; Nardelli, Federica; Binaschi, Monica; Maggi, Carlo A.; Fattori, Daniela Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 8 p. 2305 - 2308

全文：HTML全文

被引用次数: 12

摘要

We report here the strategy used in our research group to find a new class of histone deacetylase (HDAC) inhibitors. A series of N-substituted 4-alkylpiperazine and 4- alkylpiperidine hydroxamic acids, corresponding to the basic structure of HDAC inhibitors ...