Halogenation of 2-Unsubstituted and 2-Methylimidazo [4, 5-b] pyridine Derivatives

…, KY Lopatinskaya, NN Smolyar, SV Gres'ko

文献索引：Yutilov; Lopatinskaya; Smolyar; Gres'Ko Russian Journal of Organic Chemistry, 2005 , vol. 41, # 3 p. 450 - 454

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被引用次数: 3

摘要

Abstract Halogenation of 2-unsubstituted and 2-methylimidazo [4, 5-b] pyridines and their N- methyl derivatives with bromine and chlorine in acetic acid takes different pathways, depending on the acetic acid concentration. The bromination in 50% aqueous acetic acid gives only 6-bromoimidazo [4, 5-b] pyridines; bromination and chlorination of 2- unsubstituted imidazo [4, 5-b] pyridines in glacial acetic acid leads to 5, 6-dibromo ( ...