A series of 5aryl-2, 4dihydro-3H-1, 2, 4-tri~ l-3-one was evaluated for anticonvulsant activity. In general the members of this series were prepared by the alkaline cyclization of 1-aroyl-4- alkylsemicmbazides. The resulting 2-unsubstituted 3H-1, 2, 4-triazol-3-ones were then alkylated, yielding 2, 4-dialkyl-3H-1, 2, 4-triazol-3-ones, Approximately one-third of the compounds examined exhibited activity against both maximal electroshock-and ...
![1-[3-(n-butoxy)-4-methoxybenzoyl]-4-methylsemicarbazide结构式](https://image.chemsrc.com/caspic/294/129521-47-7.png)
