Organic letters

Synthesis of 2-Aminophenols and Heterocycles by Ru-Catalyzed C–H Mono-and Dihydroxylation

X Yang, G Shan, Y Rao

文献索引：Yang, Xinglin; Shan, Gang; Rao, Yu Organic Letters, 2013 , vol. 15, # 10 p. 2334 - 2337

被引用次数: 39

摘要

A novel and efficient synthesis of 2-aminophenols, 2-aminobenzene-1, 3-diols, and heterocycles through Ru-catalyzed C–H mono-and dihydroxylation of anilides has been developed with a new directing group strategy. The reaction demonstrates excellent reactivity, regioselectivity, good functional group tolerance, and high yields.

65854-91-3

4'-氯新戊酰苯胺

~16%

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~83%

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~90%

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~63%

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