Synlett

Chromatography-free Suzuki reactions using a polymer-assisted solution-phase (PASP) approach

E Vickerstaffe, AL Villard, M Ladlow, SV Ley

文献索引：Vickerstaffe, Emma; Villard, Anne-Laure; Ladlow, Mark; Ley, Steven V. Synlett, 2007 , # 8 p. 1251 - 1254

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被引用次数: 8

摘要

Abstract An efficient Suzuki coupling protocol that affords reaction products in high purity without the need for chromatography or aqueous work-up is reported. The reaction, which utilises a combination of polymer-supported reagents, can be performed under thermal or microwave heating conditions and is particularly suited to parallel synthesis.