Abstract The anti-epileptic agent remacemide hydrochloride has been prepared labelled with 14 C, from [carbonyl-14 C] acetophenone, and with 13 C from [13 C 6] benzene,[1, 2-13 C] acetyl chloride and [1-13 C] glycine.[2-3 H] Glycine was utilised to prepare remacemide labelled with tritium at low specific activity. In addition other 2 H-and high specific activity 3 H- isotopomers of the drug, and of an active metabolite of the drug, were prepared by ...
