HCV NS5B polymerase inhibitors 2: Synthesis and in vitro activity of (1, 1-dioxo-2H-[1, 2, 4] benzothiadiazin-3-yl) azolo [1, 5-a] pyridine and azolo [1, 5-a] pyrimidine …

…, SE Bailey, D Ruhrmund, L Hooi, S Misialek…

文献索引：Wang, Guangyi; Lei, Huoxing; Wang, Xiaofang; Das, Debasis; Hong, Jian; Mackinnon, Colin H.; Coulter, Thomas S.; Montalbetti, Christian A.G.N.; Mears, Richard; Gai, Xinjie; Bailey, Sarah E.; Ruhrmund, Donald; Hooi, Lisa; Misialek, Shawn; Rajagopalan, P.T. Ravi; Cheng, Robert K.Y.; Barker, John J.; Felicetti, Brunella; Schoenfeld, Dorian L.; Stoycheva, Antitsa; Buckman, Brad O.; Kossen, Karl; Seiwert, Scott D.; Beigelman, Leonid Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 15 p. 4480 - 4483

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被引用次数: 16

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... (1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl) azolo[1,5-a]pyridine and azolo[1,5-a]pyrimidine derivatives have been investigated as potential anti-HCV drugs. Their synthesis, HCV NS5B polymerase inhibition, and replicon activity are discussed. ... Synthesis of (1,1-dioxo-2H-[1,2,4] ...