Cysteine-derived organocatalyst in a highly enantioselective intramolecular Michael reaction

…, H Gotoh, T Tamura, H Yamaguchi…

文献索引：Hayashi, Yujiro; Gotoh, Hiroaki; Tamura, Tomohiro; Yamaguchi, Hirofumi; Masui, Ryouhei; Shoji, Mitsuru Journal of the American Chemical Society, 2005 , vol. 127, # 46 p. 16028 - 16029

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被引用次数: 178

摘要

Asymmetric intramolecular Michael reaction catalyzed by an organocatalyst derived from cysteine has been developed for the synthesis of chiral bicyclo [4.3. 0] nonene and cis- disubstituted cyclopentane skeletons with a creation of three or two contiguous chiral centers in good yield with high diastereo-and excellent enantioselectivities.