A new chromone and flavone synthesis and its utilization for the synthesis of potentially antitumorigenic polycyclic chromones and flavones

…, JT Hahn, M Bukowska, H Jackson

文献索引：Harvey, Ronald G.; Hahn, Jung-Tai; Bukowska, Maria; Jackson, Henry Journal of Organic Chemistry, 1990 , vol. 55, # 25 p. 6161 - 6166

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被引用次数: 20

摘要

We now report extension of this synthetic approach to the preparation of chromones and flavones and utilization of the method to prepare a series of potentially antitumorigenic polycyclic chromones and flavones. The synthetic route employed is based upon the ready availability of polycyclic phenols and the facility of their functionalization via ortho-directed metalation of their methoxymethyl ethers. The general synthetic approach (Scheme I) ...