Organic letters

A cyclotrimerization route to cannabinoids

JA Teske, A Deiters

文献索引：Teske, Jesse A.; Deiters, Alexander Organic Letters, 2008 , vol. 10, # 11 p. 2195 - 2198

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被引用次数: 55

摘要

Three members of the cannabinoid class, cannabinol, cannabinol methyl ether, and cannabinodiol, were synthesized using a microwave-mediated [2+ 2+ 2] cyclotrimerization reaction as the key step. This approach provides a high level of synthetic flexibility allowing for the facile synthesis of cannabinoid analogues.