0022-3263/86/1951-3897 $01.50/0 0 our synthetic project on orally active antifungal azoles, this structure prompted us to study the reaction of carbonyl compounds with azolylmethyl carbanions 2. Lithiation of 1-alkylazoles occurs at ring positions, 2 exceptionally at NC, of the alkyl radi~ al.~-'O 1-Methylpyrazole was lithiated at the N-methyl group in competition with the 5-position; however, 1, 5-dimethylpyrazole was lithiated at the N-methyl group. 4 ...
