Phosphorus, Sulfur, and Silicon

Synthesis and anticancer activities of some thiazole derivatives

I Kayagil, S Demirayak

文献索引：Kayagil, Ismail; Demirayak, Seref Phosphorus, Sulfur and Silicon and the Related Elements, 2009 , vol. 184, # 9 p. 2197 - 2207

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被引用次数: 10

摘要

In this study, 2-substituted 4-[3/4-(4-arylthiazole-2-yl) aminophenyl] thiazole derivatives and 2-[4-[2-substituted 4-methylthiazole-5-yl] thiazole-2-yl] amino-5-arylidenethiazoline-4-one derivatives have been synthesized. The cytotoxic and/or growth inhibitory effects of the 16 selected compounds were evaluated in vitro against approximately 66 human tumor cell lines derived from nine neoplastic diseases. Some of the compounds were found to act as ...