Tetrahedron

The reaction of acetal-type protective groups in combination with TMSOTf and 2, 2′-bipyridyl; mild and chemoselective deprotection and direct conversion to other …

…, Y Minamitsuji, O Kubo, K Senami, T Maegawa

文献索引：Fujioka, Hiromichi; Minamitsuji, Yutaka; Kubo, Ozora; Senami, Kento; Maegawa, Tomohiro Tetrahedron, 2011 , vol. 67, # 16 p. 2949 - 2960

全文：HTML全文

被引用次数: 13

摘要

A mild and chemoselective deprotection method of various acetal-type protective groups, such as MOM, MEM, BOM, and SEM ethers, has been developed. The combination of TMSOTf and 2, 2′-bipyridyl was very effective for the deprotection, and the reaction proceeded via the formation of pyridinium intermediates, which were hydrolyzed to the corresponding alcohols in good to high yields. The features of this method are mild ( ...

~93%

查看详情

查看详情

~93%

查看详情

~89%

查看详情

~87%

查看详情

~18%

查看详情

~98%

查看详情

~92%

查看详情

~95%

查看详情

~92%

查看详情

~82%

查看详情

~89%

查看详情

~84%

查看详情

~84%

查看详情

~87%

查看详情

~95%

查看详情

~85%

查看详情

~92%

查看详情

查看详情

查看详情

查看详情

~48%

查看详情

Total synthesis of cyclostellettamine C, a bispyridinium mac...

[Anan, Hideki; Seki, Norio; Noshiro, Osamu; Honda, Kazuo; Yasumuro, Kenichi; Ozasa, Teruaki; Fusetani, Nobuhiro Tetrahedron, 1996 , vol. 52, # 33 p. 10849 - 10860]

Novel Regiocontrolled Protection of 1, 2-and 1, 3-Diols via ...

[Fujioka, Hiromichi; Kubo, Ozora; Okamoto, Kazuhisa; Senami, Kento; Okitsu, Takashi; Ohnaka, Takuya; Sawama, Yoshinari; Kita, Yasuyuki Heterocycles, 2009 , vol. 77, # 2 p. 1089 - 1103]

Facile and highly selective monoacylation of symmetric diols...

[Ogawa, Haruo; Amano, Misa; Chihara, Teiji Chemical Communications, 1998 , # 4 p. 495 - 496]