Synlett

Concise total synthesis of (-)-muricatacin and (-)-iso-cladospolide B using chemoselective cross-metathesis

L Ferrie, S Reymond, P Capdevielle, J Cossy

文献索引：Ferrie, Laurent; Reymond, Sebastien; Capdevielle, Patrice; Cossy, Janine Synlett, 2007 , # 18 p. 2891 - 2893

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被引用次数: 24

摘要

Hydroxylactones of type A are found in some natural products, including (-)-muricatacin and (-)-iso-cladospolide B. The biological activities of these lactones depend on the length of the alkyl side chain, and also on the absolute configuration of the stereogenic centers within the side chain. [1] These compounds can be found in plants as well as in marine or soil fungi. For our part, we were particularly interested in synthesizing (-)-muricatacin and (-)-iso- ...