Effects of novel synthesized pyridothiazines on various guinea pig heart muscle preparations

B Schade, T Erker, M Weber, C Studenik

文献索引：Schade, Bettina; Erker, Thomas; Weber, Manuela; Studenik, Christian Biological and Pharmaceutical Bulletin, 2004 , vol. 27, # 9 p. 1364 - 1370

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被引用次数: 1

摘要

Calcium channel blockers have become important tools in the treatment of cardiovascular disorders and other diseases. Hybridization of well established calcium antagonist subclasses was an attempt to optimize their pharmacological profile. The intension of this study was to investigate the electrophysiological properties of MM 10 and MM 11 two newly synthesized compounds structurally closely related to KT-362 (5-[3-[[2-(3, 4- ...