Synthesis of substituted N??(2, 4??dioxo??1, 2, 3, 4??tetrahydroquinazolinyl) benzamides and N??(2??thiono??4??oxo??1, 2, 3, 4??tetrahydroquinazolinyl) benzamides

N Chau, Y Saegusa, Y Iwakura

文献索引：Chau, Nguyen; Saegusa, Yasuo; Iwakura, Yoshio Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 541 - 544

全文：HTML全文

被引用次数: 21

摘要

Abstract Substituted N-(2, 4-Dioxo-1, 2, 3, 4-tetrahydroquinazolinyl) benzamides (3a-g) and substituted N-(2-Thiono-4-oxo-1, 2, 3, 4-tetrahydroquinazolinyl) benzamides (4a-g) were synthesized in one step from the reaction of methyl anthranilate with 2-aryl-1, 3, 4- oxadiazolin-5-ones (1a-g) and 2-aryl-1, 3, 4-oxadiazoline-5-thiones (2a-g), respectively, in m-cresol at 150–160. Alternative routes leading to the formation of 3a and 4a are also ...