1, 2, 4??Triazines. 5. Regioselective N2??amination of 3??methylthio??1, 2, 4??triazin??5 (2H)??ones. A new efficient synthesis of [1, 2, 4] triazolo [2, 3??b][1, 2, 4] triazin??7 (1H) …

Y Sanemitsu, Y Nakayama…

文献索引：Sanemitsu, Yuzuru; Nakayama, Yoshinori; Shiroshita, Masao Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1583 - 1584

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被引用次数: 6

摘要

Abstract A regioselective synthesis of 2-amino-1, 2, 4-triazinones (3a-b) is reported, by reaction of 3-methylthio-1, 2, 4-triazinones (1a-b) with O-(2, 4-dinitrophenyl) hydroxylamine (2), as an amino transfer agent. A spectroscopic study and an unequivocal synthesis of 2- amino-4-methyl-6-phenyl-1, 2, 4-triazinone (8a) has shown the site of amination to be N2 of the 1, 2, 4,-triazinone ring. Subsequent reaction of 2-amino-1, 2, 4-triazinone (3b) with ...