A new synthesis of. beta.-lactams: 3-oxo-6-thia-2-azabicyclo [2.2. 0] hexanes via photochemical reactions of N-(thiobenzoyl) methacrylamides

M Sakamoto, Y Omote, H Aoyama

文献索引：Sakamoto, Masami; Omote, Yoshimori; Aoyama, Hiromu Journal of Organic Chemistry, 1984 , vol. 49, # 2 p. 396 - 397

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被引用次数: 23

摘要

A New Synthesis of P-Lactams: 3-0~0-6-thia-2-azabicyclo[2.2.0 ]hexanes via Photochemical Reactions of N-(Thiobenzoy1)methacrylamides Summary: Irradiation of N-(thiobenzoy1)methacrylamides in benzene gave thietan-fused @-lactams in good yields, and these were converted to other p-lactams by reduction or oxidation. ... Sir: The synthesis of @-lactam compounds has been of continuing interest for many years because of the medical importance of penicillin and ...