Synthesis using pyridinium anhydrobases, preparation of indolizine derivatives

P Molina, PM Fresneda…

文献索引：Molina, P.; Fresneda, P. M.; Lajara, M. C. Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 113 - 119

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被引用次数: 9

摘要

Abstract A number of derivatives of indolizine ring system have been prepared from 1- substituted 4, 6-diphenyl-2-phenacylidene-1, 2-dihydropyridines either by metallation with LDA or acylation and further basic treatment. Similarly, I-arylmethyl-4, 6-diphenyl-2- dicyanomethylene-1, 2-dihydropyridines by action of LDA undergo cyclization to the corresponding 2-amino-1-cyano-3-aryl indolizines.