Tetrahedron 2018-04-03

Synthesis of N-Sulfonylformamidines by tert-butyl Hydroperoxide–Promoted, metal-free, direct oxidative dehydrogenation of aliphatic amines

Ayijiamali Rouzi, Ruzeahong Hudabaierdi, Abudureheman Wusiman

文献索引：10.1016/j.tet.2018.03.074

摘要

A direct and convenient metal-free method to prepare sulfonyl amidines in the presence of aqueous tert-butyl hydroperoxide (T-HYDRO) has been developed. Different tertiary and secondary amines were tested for compatibility with the oxidative conditions and could be coupled with sulfonyl azides to form the corresponding amidines in moderate to good yields.