Synthesis 2018-04-03

One-Step O-Demethyl-Decarboxylation of ortho-Methoxy Aromatic Carboxylic Acids

Cahiez, Gérard, Moyeux, Alban, Zhou, Edouard, Poizat, Maël

文献索引：10.1055/s-0036-1591912

摘要

A highly selective decarboxydemethylation of o-methoxyarenecarboxylic acids is described. The reaction takes place in DMPU at 170 °C in the presence of TMEDA and iron powder. A similar reaction has not been reported until now.