Tetrahedron

Synthesis of novel halo-oxybispyridines, new building blocks in cholinergic medicinal chemistry

AS Voisin, A Bouillon, JC Lancelot, A Lesnard, S Rault

文献索引：Voisin, Anne Sophie; Bouillon, Alexandre; Lancelot, Jean-Charles; Lesnard, Aurelien; Rault, Sylvain Tetrahedron, 2006 , vol. 62, # 25 p. 6000 - 6005

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被引用次数: 13

摘要

This paper describes a method for the preparation of oxybispyridines bearing several halogens, which could be further transformed into other functional groups thus giving access to libraries with the bis-pyridyl ether moiety as the common structural feature of interest in cholinergic medicinal chemistry. Scope and limitation of the method are outlined.