Chemistry and physics of lipids

A gas-liquid chromatographic method for steric analysis of 2-hydroxy, 3-hydroxy, and 2, 3-dihydroxy acids

LY Zhang, M Hamberg

文献索引：Zhang, Lian-Ying; Hamberg, Mats Chemistry and Physics of Lipids, 1994 , vol. 74, # 2 p. 151 - 161

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被引用次数: 8

摘要

A method was developed for assignment of the absolute configuration of oxylipin-derived 2-hydroxy acids, 3-hydroxy acids and 2,3-dihydroxy acids. The monohydroxy acids were converted into diastereomeric (PAP) derivatives by coupling to the methyl ester of l-phenylalanine followed by propionylation, whereas the 2,3-dihydroxy acids were derivatized by treatment with l-phenylalanine methyl ester followed by acetone and perchloric acid, to afford diastereomeric (IAP) ...