Monoamine oxidase inhibitors. The synthesis and evaluation of a series of substituted alkylhydrazines

DJ Drain, JGB Howes, R Lazare…

文献索引：Drain,D.J. et al. J. Med. Chem., 1963 , vol. 6, p. 63 - 69

全文：HTML全文

被引用次数: 8

摘要

Method B.-To a warm solution of 0.02 mole of an ethyl N-nrylsulfonylcarbamate in 75 ml. of toluene was added, dropwise, with stirring, a solution of 0.022 mole of the desired amine in 25 ml. of toluene. The mixture was refluxed for 3 hr. and cooled. If the product crystallized, it was isolated by filtration; otherwise, the toluene was removed under reduced pressure. The product was crystallized from dilute ethanol, with acidification aith 57, hydrochloric acid ...