Palladium-catalyzed decarboxylative cross-coupling reaction between heteroaromatic carboxylic acids and aryl halides

…, N Guimond, KH Thesen, P Forgione

文献索引：Bilodeau, Francois; Brochu, Marie-Christine; Guimond, Nicolas; Thesen, Kris H.; Forgione, Pat Journal of Organic Chemistry, 2010 , vol. 75, # 5 p. 1550 - 1560

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被引用次数: 105

摘要

A full overview of the decarboxylative cross-coupling reaction between heteroaromatic carboxylic acids and aryl halides is described. This transformation employs palladium catalysts with short reaction times providing facile synthesis of aryl-substituted heteroaromatics. The effect of each reaction parameter including solvent, base, and additive employed as well as the full substrate scope of this transformation are reported. ...

6973-60-0

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