Prevention of drug-induced memory impairment by immunopharmacotherapy

…, L Qi, CL Levy, AJ Roberts, TJ Dickerson…

文献索引：Treweek, Jennifer B.; Sun, Chengzao; Mayorov, Alexander V.; Qi, Longwu; Levy, Coree L.; Roberts, Amanda J.; Dickerson, Tobin J.; Janda, Kim D. Journal of Medicinal Chemistry, 2008 , vol. 51, # 21 p. 6866 - 6875

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被引用次数: 5

摘要

One approach to treating drug abuse uses antidrug antibodies to immunize subjects against the illicit substance rather than administering therapeutics that target the specific CNS site of action. At present, passive vaccination has recognized efficacy in treating certain gross symptoms of drug misuse, namely, motor activation, self-administration, and overdose. However, the potential for antibodies to prevent drug-induced changes involving finer ...