Tetrahedron

Synthesis of two stereoisomeric polydentate ligands, trans and cis cyclopentane-1, 2-diaminotetraacetic acids, and complexation by 111 In and 153 Sm

SG Gouin, JF Gestin, K Joly, A Loussouarn, A Reliquet…

文献索引：Gouin, Sebastien G; Gestin, Jean-Francois; Joly, Kevin; Loussouarn, Anthony; Reliquet, Alain; Claude Meslin, Jean; Deniaud, David Tetrahedron, 2002 , vol. 58, # 6 p. 1131 - 1136

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被引用次数: 23

摘要

Two polyaminocarboxylic acid chelating agents were synthesized. Complexation properties regarding 111In and 153Sm, two radionuclides suitable for applications in immunoscintigraphy and radioimmunotherapy were investigated. The synthesis of aminodiacetic acid derivatives 7a and 7b involved preliminary stereoselective synthesis of the corresponding amines, cis and trans cyclopentane-1, 2-diamines. 111In labelling ...