The synthesis of hydroxylamine derivatives possessing hypocholesteremic activity

BJ Ludwig, F Dursch, M Auerbach…

文献索引：Ludwig,B.J. et al. Journal of Medicinal Chemistry, 1967 , vol. 10, p. 556 - 564

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被引用次数: 18

摘要

L+ RIONR, CONXY K versions at room temperature. Benzyl chlorides and higher aralkyl halides usually required several hours of reflux for completion of the reaction. Small quantities of the corresponding ethyl ethers were always obtained as by-products, these ethers being formed by aralkylation of the alcoholic solvent. These lower boiling ethers could be readily separated from the reaction mixture by distillation. A 1: 1 molar ratio of ...