Abstract The preparative aspects of the addition of nucleophiles to alkyne-derivatives having both push-and pull-groups (1) are discussed: The addition of primary and secondary amines as well of aliphatic alcohols to the alkyne-derivatives 1 in most cases predominantly yields the Michael-adducts 2–10. The importance of a side-reaction consisting in an addition of amines to C (2) of the alkyne-derivatives 1 increases in the series 1c≪ 1b< 1a and is ...
