Tetrahedron

Theoretical and experimental studies of the 3-aza-Claisen rearrangement

JC Gilbert, KR Cousins

文献索引：Gilbert, John C.; Cousins, Kimberley R. Tetrahedron, 1994 , vol. 50, # 36 p. 10671 - 10684

全文：HTML全文

被引用次数: 10

摘要

Semiempirical calculations support a spin-paired chair-like TS for the 3-aza-Claisen rearrangement, and yield the prediction that an anionic substituent on the nitrogen atom reduces the activation energies for the rearrangement. Attempts to demonstrate this experimentally have been unsuccessful.