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举例 :可输入Filippa Pettersson 或者 Cancer Res. 75(6) , 1102-12, (2015) 或者10.1002/anie.201600521

Carbohydrate research

Syntheses of 1-(5-deoxy-β-d-arabino-hexofuranosyl) cytosine

M Iwakawa, OR Martin, WA Szarek

文献索引：Iwakawa, Masaharu; Martin, Olivier R.; Szarek, Walter A. Carbohydrate Research, 1983 , vol. 121, p. 99 - 108

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被引用次数: 5

摘要

Abstract 1-(5-Deoxy-β-d-arabino-hexofuranosyl) cytosine (4′-homoara-C)(11), a higher homolog of the antileukemic agent ara-C (1-β-d-arabinofuranosylcytosine), was prepared by two independent routes. The first one involved the inversion of configuration at C-2′ of the d-ribo epimer (1-(5-deoxy-β-d-ribo-hexofuranosyl) cytosine, 4′-homocytidine) by the diphenylcarbonate technique; the 5-deoxy-d-ribo-hexofuranosyl moiety of 4′- ...

4-[2-(4-methoxyphenyl)-2-oxoethyl]benzonitrile结构式

4-[2-(4-methoxy...

~%

1-(5-deoxy-beta-D-hexofuranosyl)cytosine结构式

1-(5-deoxy-beta...

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5,6-dideoxy-1,2-O-isopropylidene-3-O-p-tolylsulfonyl-α-D-ribo-hex-5-enofuranose结构式

5,6-dideoxy-1,2...

~%

1-(5-deoxy-beta-D-hexofuranosyl)cytosine结构式

1-(5-deoxy-beta...

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3-[1,2-bis-(4-methylphenyl)sulfonyloxyethyl]-7,7-dimethyl-4-(4-methylphenyl)sulfonyloxy-2,6,8-trioxabicyclo[3.3.0]octane结构式

3-[1,2-bis-(4-m...

~%

1-(5-deoxy-beta-D-hexofuranosyl)cytosine结构式

1-(5-deoxy-beta...

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1,2-O-isopropylidene-α-D-glucofuranose结构式

1,2-O-isopropyl...

~%

1-(5-deoxy-beta-D-hexofuranosyl)cytosine结构式

1-(5-deoxy-beta...

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5-deoxy-1,2-O-isopropylidene-3-O-p-tolylsulfonyl-α-D-ribo-hexofuranose结构式

5-deoxy-1,2-O-i...

~%

1-(5-deoxy-beta-D-hexofuranosyl)cytosine结构式

1-(5-deoxy-beta...

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1-(O2-acetyl-O3,O6-dibenzoyl-β-D-ribo-5-deoxy-hexofuranosyl)-4-acetylamino-1H-pyrimidin-2-one结构式

1-(O2-acetyl-O3...

~81%

1-(5-deoxy-beta-D-hexofuranosyl)cytosine结构式

1-(5-deoxy-beta...

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5-Deoxy-1-O,2-O-isopropylidene-3-O,6-O-dibenzoyl-α-D-ribo-hexofuranose结构式

5-Deoxy-1-O,2-O...

~%

1-(5-deoxy-beta-D-hexofuranosyl)cytosine结构式

1-(5-deoxy-beta...

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1,2-di-O-acetyl-3,6-di-O-benzoyl-5-deoxy-D-ribo-hexofuranose结构式

1,2-di-O-acetyl...

~%

1-(5-deoxy-beta-D-hexofuranosyl)cytosine结构式

1-(5-deoxy-beta...

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5-deoxy-1,2-O-isopropylidene-α-D-ribo-hexofuranose结构式

5-deoxy-1,2-O-i...

~%

1-(5-deoxy-beta-D-hexofuranosyl)cytosine结构式

1-(5-deoxy-beta...

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1-(5-deoxy-beta-D-hexofuranosyl)cytosine结构式

1-(5-deoxy-beta...

~50%

4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(2-hydroxyethyl)oxolan-2-yl]pyrimidin-2-one结构式

4-amino-1-[(2R,...

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4-N-acetyl-1-(2,6-di-O-acetyl-5-deoxy-3-O-p-tolylsulfonyl-β-D-xylo-hexofuranosyl)cytosine结构式

4-N-acetyl-1-(2...

~99%

4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(2-hydroxyethyl)oxolan-2-yl]pyrimidin-2-one结构式

4-amino-1-[(2R,...

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4-[2-(4-methoxyphenyl)-2-oxoethyl]benzonitrile结构式

4-[2-(4-methoxy...

~%

4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(2-hydroxyethyl)oxolan-2-yl]pyrimidin-2-one结构式

4-amino-1-[(2R,...

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5-deoxy-1,2-O-isopropylidene-3-O-p-tolylsulfonyl-α-D-xylo-hexofuranose结构式

5-deoxy-1,2-O-i...

~%

4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(2-hydroxyethyl)oxolan-2-yl]pyrimidin-2-one结构式

4-amino-1-[(2R,...

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5-Deoxy-1-O,2-O-isopropylidene-3-O,6-O-dibenzoyl-α-D-ribo-hexofuranose结构式

5-Deoxy-1-O,2-O...

~%

4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(2-hydroxyethyl)oxolan-2-yl]pyrimidin-2-one结构式

4-amino-1-[(2R,...

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1,2-di-O-acetyl-3,6-di-O-benzoyl-5-deoxy-D-ribo-hexofuranose结构式

1,2-di-O-acetyl...

~%

4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(2-hydroxyethyl)oxolan-2-yl]pyrimidin-2-one结构式

4-amino-1-[(2R,...

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5-deoxy-1,2-O-isopropylidene-α-D-ribo-hexofuranose结构式

5-deoxy-1,2-O-i...

~%

4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(2-hydroxyethyl)oxolan-2-yl]pyrimidin-2-one结构式

4-amino-1-[(2R,...

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5,6-dideoxy-1,2-O-isopropylidene-3-O-p-tolylsulfonyl-α-D-ribo-hex-5-enofuranose结构式

5,6-dideoxy-1,2...

~%

4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(2-hydroxyethyl)oxolan-2-yl]pyrimidin-2-one结构式

4-amino-1-[(2R,...

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1,2,6-tri-O-acetyl-5-deoxy-3-O-p-tolylsulfonyl-D-xylo-hexofuranose结构式

1,2,6-tri-O-ace...

~%

4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(2-hydroxyethyl)oxolan-2-yl]pyrimidin-2-one结构式

4-amino-1-[(2R,...

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3-[1,2-bis-(4-methylphenyl)sulfonyloxyethyl]-7,7-dimethyl-4-(4-methylphenyl)sulfonyloxy-2,6,8-trioxabicyclo[3.3.0]octane结构式

3-[1,2-bis-(4-m...

~%

4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(2-hydroxyethyl)oxolan-2-yl]pyrimidin-2-one结构式

4-amino-1-[(2R,...

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1,2-O-isopropylidene-α-D-glucofuranose结构式

1,2-O-isopropyl...

~%

4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(2-hydroxyethyl)oxolan-2-yl]pyrimidin-2-one结构式

4-amino-1-[(2R,...

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5-deoxy-1,2-O-isopropylidene-3-O-p-tolylsulfonyl-α-D-ribo-hexofuranose结构式

5-deoxy-1,2-O-i...

~%

4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(2-hydroxyethyl)oxolan-2-yl]pyrimidin-2-one结构式

4-amino-1-[(2R,...

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1-(O2-acetyl-O3,O6-dibenzoyl-β-D-ribo-5-deoxy-hexofuranosyl)-4-acetylamino-1H-pyrimidin-2-one结构式

1-(O2-acetyl-O3...

~%

4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(2-hydroxyethyl)oxolan-2-yl]pyrimidin-2-one结构式

4-amino-1-[(2R,...

查看详情