Green Chemistry

Iron phthalocyanine as an efficient and versatile catalyst for N-alkylation of heterocyclic amines with alcohols: one-pot synthesis of 2-substituted benzimidazoles, …

M Bala, PK Verma, U Sharma, N Kumar, B Singh

文献索引：Bala, Manju; Verma, Praveen Kumar; Sharma, Upendra; Kumar, Neeraj; Singh, Bikram Green Chemistry, 2013 , vol. 15, # 6 p. 1687 - 1693

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被引用次数: 51

摘要

An efficient and versatile iron phthalocyanine catalyzed method has been developed for N- alkylation of various amines with alcohols. Readily available alcohols were used as alkylating agents for direct N-alkylation of aminobenzothiazoles, aminopyridines and aminopyrimidines. N-Alkylation of ortho-substituted anilines (–NH 2,–SH and–OH) led to the synthesis of 2-substituted benzimidazoles, benzothiazoles and benzoxazoles in one pot.