Magnesium??Mediated Benzothiazole Activation: A Room??Temperature Cascade of C H Deprotonation, C C Coupling, Ring??Opening, and Nucleophilic Addition …

…, AR Kennedy, Z Livingstone, L Russo…

文献索引：Blair, Victoria L.; Clegg, William; Kennedy, Alan R.; Livingstone, Zoe; Russo, Luca; Hevia, Eva Angewandte Chemie - International Edition, 2011 , vol. 50, # 42 p. 9857 - 9860

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被引用次数: 20

摘要

Five-membered ring aromatic heterocycles, in particular 1, 3-azoles, are common building blocks for the synthesis of a multitude of natural products, pharmaceuticals, and other biologically active molecules.[1] An invaluable synthetic tool which facilitates the incorporation of these heterocyclic rings into more complex organic scaffoldings is deprotonative metalation.[2] Thus, 1–3 azoles can be readily deprotonated at the C2 ...