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Poly (ethylene glycol)(PEG-400) as an alternative reaction solvent for the synthesis of some new 1-(4-(4′-chlorophenyl)-2-thiazolyl)-3-aryl-5-(2-butyl-4-chloro-1H- …

BS Dawane, SG Konda, GG Mandawad…

文献索引:Dawane, Bhaskar S.; Konda, Shankaraiah G.; Mandawad, Gajanan G.; Shaikh, Baseer M. European Journal of Medicinal Chemistry, 2010 , vol. 45, # 1 p. 387 - 392

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被引用次数: 102

摘要

Several 1-(4-(4′-chlorophenyl)-2-thiazolyl)-3-aryl-5-(2-butyl-4-chloro-1H-imidazol-5yl)-2- pyrazoline derivatives were prepared by the base catalyzed treatment of appropriate chalcones with 4-(4′-chlorophenyl)-2-hydrazino-thiazole in poly (ethylene glycol)(PEG- 400) as an alternative reaction solvent. All the synthesized compounds were tested for their antimicrobial activities against Escherichia coli (MTCC 2939), Salmonella typhi (MTCC 98 ...