Stereoselective ring contraction of 2, 5-diketopiperazines: An innovative approach to the synthesis of promising bioactive 5-membered scaffolds

T Coursindel, A Restouin, G Dewynter, J Martinez…

文献索引：Coursindel, Thibault; Restouin, Audrey; Dewynter, Georges; Martinez, Jean; Collette, Yves; Parrot, Isabelle Bioorganic Chemistry, 2010 , vol. 38, # 5 p. 210 - 217

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被引用次数: 14

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Ring contraction of 2,5-diketopiperazines by TRAL-alkylation led us to the stereoselective synthesis of original pyrrolidine-2,4-diones, a novel series of promising molecules with moderate anti-proliferative activity on breast cancer cells. ... Ring contraction of 2,5-diketopiperazines by TRAL- ...