Synthesis of 4-(3H)-quinazolinones by microwave assisted tandem reaction and evaluation of their antibacterial and antifungal activities

…, Y Zulykama, K Girija, S Murugesh…

文献索引：Priya, M. Gnana Ruba; Zulykama; Girija; Murugesh; Perumal Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2011 , vol. 50, # 1 p. 98 - 102

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被引用次数: 12

摘要

Abstract: A one-pot synthesis of quinazolinone derivatives from the reaction of anthranilic acid and primary aromatic amines with Vilsmeier reagent (DMF/POCl 3) has been carried out. The reaction occurred in a few minutes under microwave irradiation providing good yields. All the synthesized compounds have been screened for their in vitro antibacterial activity against S. aureus, S. epidermis, B. cereus, B. subtilis, Ps. aureus, Kl. pneumonia ...