New Facile Synthesis of 7??Hydroxy??6??amino??4??substituted Benzopyran??2??ones

G Evagelos, PP Maria, K Michael…

文献索引：Gikas, Evagelos; Parissi-Poulou, Maria; Kazanis, Michael; Vavagianis, Andreas Synthetic Communications, 2004 , vol. 34, # 22 p. 4233 - 4242

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被引用次数: 1

摘要

Abstract A new facile synthesis of 6??amino??7??hydroxy??4??substituted benzopyranones is described through the von Pechmann reaction. The yields obtained were high, and the proposed methodology leads to pure products. The selectivity of formation of the desired products can be attributed to the formation of an intramolecular hydrogen bond, which leads to reduced reactivity of the 2??hydroxyl group.