Tetrahedron Letters

Preparation of sulfonamides from N-silylamines

RR Naredla, DA Klumpp

文献索引：Naredla, Rajasekhar Reddy; Klumpp, Douglas A. Tetrahedron Letters, 2013 , vol. 54, # 45 p. 5945 - 5947

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被引用次数: 2

摘要

Abstract Sulfonamides have been prepared in high yields by the reactions of N-silylamines with sulfonyl chlorides and fluorides. In a competition experiment, the sulfonyl chlorides were found to be far more reactive than sulfonyl fluorides. The chemistry may be used to prepare aliphatic, aromatic, tertiary, secondary, and primary sulfonamides. It may also be done in the absence of solvent and the byproduct trimethylsilyl chloride recovered in good ...