Characterization of proton-transfer catalysis by serum albumins

F Hollfelder, AJ Kirby, DS Tawfik…

文献索引：Kirby, Anthony J.; Williams, Nicholas H. Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1994 , # 4 p. 643 - 648

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被引用次数: 64

摘要

Two independent investigations of catalysis by BSA and other serum albumins are combined to provide detailed insight into the mechanism of a classical proton-transfer reaction taking place on the surface of a protein. The Kemp elimination involves the general