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Tetrahedron

Benzotriazole: a novel synthetic auxiliary

AR Katritzky, S Rachwal, GJ Hitchings

文献索引:Katritzky, Alan R.; Rachwal, Stanislaw; Hitchings, Gregory J. Tetrahedron, 1991 ,  vol. 47,  # 16-17  p. 2683 - 2732

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被引用次数: 257

摘要

Benzotriazole and aldehydes react reversibly to give addition products: in the presence of amines and other NH-compounds water can be eliminated to form products of type Bt-CHR- NR′ R ″. The latter are versatile intermediates for the preparation of primary, secondary, and tertiary amines and in the alkylation of hydroxylamines, hydrazines, amides, thioamides, and sulfonamides. Polyfunctional amines and other polyfunctional compounds can also ...