2, 6-Dimethyl-4-nitrochlorobenzene (1) is an intermediate of potential use for the preparation of a variety of biologically active molecules.'Despite the utility of this compound, it remains poorly known in the literature, with details of its preparation confined to three patents and one journal articleG2 Each of these syntheses proceeds in the same manner, starting with 2, 6-dimethylaniline (2) and carrying out four steps:(1) N-protection;(2) nitration;(3) N- ...