Use of polar picolyl protecting groups in peptide synthesis

…, G Romero, C Garcia-Echeverria, J Claret…

文献索引：Rizo, Josep; Albericio, Fernando; Romero, Guillermo; Garcia-Echeverria, Carlos; Claret, Josep; et al. Journal of Organic Chemistry, 1988 , vol. 53, # 22 p. 5386 - 5389

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被引用次数: 20

摘要

Summary: Protection of serine and threonine side chains with the 4-picolyl group and aspartic and glutamic acids with the 3-picolyl group is described. Picolyl-protected peptide segments are markedly more polar than benzylprotected analogues, which can facilitate their purification.