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Coumarins: Facile and Expeditious Synthesis via Keggin??Type Heteropolycompounds under Solvent??Free Condition

E Rafiee, A Fakhri, M Joshaghani

文献索引:Rafiee, Ezzat; Fakhri, Akram; Joshaghani, Mohammad Journal of Heterocyclic Chemistry, 2013 , vol. 50, # 5 p. 1121 - 1128

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被引用次数: 2

摘要

Abstract Different Keggin-type heteropolycompounds were used in Pechmann reaction to obtain biologically active coumarins. Effect of solvent, catalyst loading, and molar ratios of substrates was studied to introduce the best reaction condition. The optimized reaction condition was extended to Pechmann reaction of methylacetoacetate with various monohydric and polyhydric phenols. This rapid procedure afforded structurally diverse ...