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Synthesis of possible metabolites of chlorpromazine. I. 7??hydroxy derivatives of chlorpromazine, nor1??chlorpromazine and nor2??chlorpromazine

EA Nodiff, S Ina, N Oda, T Hayazaki…

文献索引:Nodiff,E.A. et al. Journal of Heterocyclic Chemistry, 1967 , vol. 4, p. 239 - 245

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被引用次数: 11

摘要

Abstract The title compounds and various derivatives have been prepared as analytical standards for the identification of chlorpromazine metabolites in biological materials. Additional evidence is presented for the existence of a halogen-induced Smiles rearrangement in the phenothiazine series.