The N-substituted 3-nitrophthalimides are known to pos- sess antibacterial [ 1], analgesic [2], and vasodilative [3] activ- ity. These compounds can be synthesized by heating 3-nitro- phthalic anhydride with amines either without solvent [4] or in acetic acid [5]. / Below we will show that N-substituted 3-Mitro- phthalimides are conveniently obtained by cyclocondensation of 3-nitrophthalic acid (I) with amines in the presence of a two-component reagent system CISiMe3- DMF. ...
![Acetic acid,2-[[(1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl)methyl]thio]结构式](https://image.chemsrc.com/caspic/093/4874-01-5.png)
