Bulletin of the Chemical Society of Japan

One-pot two-step solvent-free rapid and clean synthesis of 2-(substituted amino) pyrimidines by microwave irradiation

S Goswami, A Hazra, S Jana

文献索引：Goswami, Shyamaprosad; Hazra, Anita; Jana, Subrata Bulletin of the Chemical Society of Japan, 2009 , vol. 82, # 9 p. 1175 - 1181

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被引用次数: 11

摘要

A series of diversely 2-(substituted amino) pyrimidines (along with ring substitution) has been synthesized under solvent-and catalyst-free microwave conditions from substituted guanidines and β-diketones. The substituted guanidines are synthesized from (S)- methylisothiourea sulfate and different amines (various alkyl, aryl, or heterocyclic and also chiral amines) under microwave irradiation. These two-step reactions are performed in ...